Gene name:
IGFBP2 (BP2;IBP2) ;
Protein name:
Insulin-like growth factor-binding protein 2 (IBP-2;IGF-binding protein 2;IGFBP-2) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds IGF2 more than IGF1.
Function:
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular Location:
Secreted
Protein Attributes:
50:
MLPRVGCPAL | PLPPPPLLPL | LLLLLGASGG | GGGARAEVLF | RCPPCTPERL |
100:
AACGPPPVAP | PAAVAAVAGG | ARMPCAELVR | EPGCGCCSVC | ARLEGEACGV |
150:
YTPRCGQGLR | CYPHPGSELP | LQALVMGEGT | CEKRRDAEYG | ASPEQVADNG |
200:
DDHSEGGLVE | NHVDSTMNML | GGGGSAGRKP | LKSGMKELAV | FREKVTEQHR |
250:
QMGKGGKHHL | GLEEPKKLRP | PPARTPCQQE | LDQVLERIST | MRLPDERGPL |
300:
EHLYSLHIPN | CDKHGLYNLK | QCKMSLNGQR | GECWCVNPNT | GKLIQGAPTI |
325:
RGDPECHLFY | NEQQEARGVH | TQRMQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Bovine
Chicken
Pig
Human
ELISA Kit for Human IBP-2
ELISA Kit for Human IBP-2
ELISA Kit for Human IBP-2
ELISA Kit for Human IBP-2
ELISA Kit for Human IBP-2
ELISA Kit for Human IBP-2
Polyclonal Antibody for Human IBP-2
Polyclonal Antibody for Human IBP-2
Polyclonal Antibody for Human IBP-2
Polyclonal Antibody for Human IBP-2
Polyclonal Antibody for Human IBP-2
Polyclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
Monoclonal Antibody for Human IBP-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Fetal liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 37-74
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Placenta .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Retina .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Placenta .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Placenta .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASP-137
8.
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
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Nature434:724-731(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
tissue :
Ovary .
tissue :
Uterus .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 40-58;INTERACTION WITH IGF2;GLYCOSYLATION
tissue :
Cerebrospinal fluid .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IGF1-BINDING;DOMAIN;MUTAGENESIS OF 216-LYS--ARG-219 AND ASP-303
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 220-325;DISULFIDE BONDS